Now Reading
Best Quality Vitamin & Supplement Brands

Best Quality Vitamin & Supplement Brands

Zack West
  • The FDA doesn't hold supplement manufacturers to the same standards as food and pharmaceutical companies. Knowing which ones go the extra mile to assure product purity is essential to avoid buying potentially dangerous products.
optimus medica best supplement brands banner

Vitamins and supplements can be essential tools on one’s path to better health. The FDA doesn’t regulate dietary supplements the same way as pharmaceuticals which makes it a paramount concern to only buy from top quality supplement brands.

Links on this page my earn us a commission. Read our Advertising Disclosure to learn more.

I’ve taken more supplements, from more supplement brands, for more reasons, than I can recall. I’ll not ever presume to offer the final word on which brand is the best. What I will offer is a list of the brands I’ve come to regard as the best options for buying supplements, with a brief description of each.

Best Supplement Brands

Below you’ll find a list of the supplement brands I’ve come to know and love. There are plenty of other quality brands out there but these companies to offer quality products, have large catalogs to choose from, and have reasonable availability. After all, what good is a companies quality assurance if you aren’t able to buy their products? In no particular order:

NOW Foods

NOW Foods is perhaps the best all-around supplement brand there is. They produce high-quality products at very affordable products and are available just about anywhere supplements are sold. They’re unbelievably transparent about the certifications their products carry, including USDA Organic, QAI Organic, Non-GMO, and GMP practices. As a company, they continue to demonstrate their dedication to improving nutritional science, consumer safety practices, and educating the public. They have become one of my go-to brands—in stores or online.

Type: Consumer Brand

Quality: High

Price: Medium

Availability: Online and Local Stores

Parent Company: NOW Health Group, Inc.

Now Foods Supplements Logo Wallpaper Optimus medida
NOW Foods is a remarkable company. They've dedicated themselves to improving industry quality standards and strive to produce the highest possible quality. Their products are a rare balance of super high quality and affordability. NOW Foods operates their own NPA GMP-Certified manufacturing facilities and are available wherever supplements are sold.
5
Rating
Available Online

Thorne Research

Thorne Research has a dedicated team of scientific advisors, their own dedicated laboratory and research facilities, and is a pioneer in the field of nutritional science. Their products are produced in NSF Registered GMP facility that is also NSF Certified for Sport. I’ve used many Thorne products over the years and have always felt they offer a higher purity. For example, I had to lower my daily magnesium dose when I switched to Thorne. Apparently, Thorne’s was that much better absorbed! Their amino acid blends are particularly wonderful in my opinion.

Type: Practitioner Brand

Price: High

Quality: High

Availability: Doctor, Authorized Re-Sellers, Direct

Parent Company: Merged w/ Diversified Natural Products (DNP)

thorne research supplements
Thorne Research is among the best supplement brands on the market today. Their extensive catalog of nutritional products has been formulated with support from their scientific advisory board and dedicated on-site laboratories.
5
Rating
Available Online

Life Extension

Life Extension has been a beacon of quality and advocacy in the natural products industry for more than 40 years. They have a dedicated scientific advisory board, operate their own NSF Registered GMP manufacturing facility, and produce incredibly affordable supplements. Life Extension is one of my go-to brands when shopping in local stores. They also have an extensive catalog of in-depth health articles to help better understand the complexities (and simplicities) of optimal health.

Type: Consumer Brand

Quality: Medium

Price: Medium

Availability: Online and Local Stores

Parent Company: Quality Supplements and Vitamins Inc.

Life Extension Supplements Logo wallpaper optimus medica
Life Extension has worked tirelessly to establish themselves as advocates of better nutrition and health. Their catalog features a large lineup of quality-formulated supplements that are among the best you'll find in local stores. They operate their own NSF Registered GMP facility.
4.5
Rating
Available Online

Pure Encapsulations

Pure Encapsulations is a practitioner channel brand with a large catalog. They have lots of isolated compounds such as magnesium glycinate and also formulated blends such as multivitamins. Pure Encapsulations is NSF Registered GMP, GFCO-Certified Gluten-Free, and assured to be free of common allergens. Their products are self-certified as Non-GMO. I’ve used a lot of their mineral supplements and amino acids over the years and have always been very happy with the quality.

Type: Practitioner Brand

Price: High

Quality: High

Availability: Doctor, Authorized Re-Sellers

Parent Company: Atrium, Inc (Nestle, Inc. Subsidiary)

pure encapsulations supplements
4.5
Overall
Available Online

Herb Pharm

Herb Pharm is my favorite brand for herbal extracts (tinctures) and has an incredible catalog of products to choose from. Their ingredients are usually organic and non-GMO, are sourced through ethical guidelines from local farmers around the world, and even use wildcraft-harvesting techniques to assure maximum potency. Many of their products are available in either grain alcohol or vegetable glycerine suspensions. I’ve noted benefits from their products when other brands didn’t seem to do much at all.

Type: Consumer Brand

Price: Medium

Quality: High

Availability: Online, Direct, Local Stores

Parent Company: Herb Pharm, LLC

herb pharm supplements logo banner
Herb Pharm offers a catalog of herbal tinctures made from high-quality, Organic & Non-GMO when possible, ingredients. They practice sustainable growing and harvesting and their products reflect the highest attention to quality assurance practices.
5
Rating
Available Online

Solgar

Solgar is possibly the highest-quality supplement brand one can expect to find in local stores. Their products are NPA GMP-Certified, often contain USDA Certified Organic Ingredients, are sourced from whole-food ingredients, and are packaged in dark amber bottles to avoid trace levels of toxins and preserve potency. The best part? They’re affordable! I usually stick to practitioner brands I’ve ordered online but when I need something from the local health food store Solgar is a brand I trust to deliver a quality product.

Type: Consumer Brand

Quality: Medium/High

Price: Medium

Availability: Online, Local Stores

Parent Company: Nature’s Bounty (NBTY)

solgar supplements logo banner optimus medica
Solgar is an NPA Certified GMP supplement manufacturer dedicated to product quality like few other brands. Their products are free of allergens, artificial ingredients, and come in amber glass bottles to preserve potency and better assure product quality. They are easily one of the best supplement brands one can find in local stores.
5
Rating
Available Online

Gaia Herbs

Gaia Herbs has set the standard for plant-based medicine over the last 25 years. They offer a consumer line of products and a professional line, targeting more specific health needs—both produced under the highest of quality standards. They own and operate a farm in the Mountains of North Carolina from which their ingredients are sourced. Gaia Herbs is  B-Corp of whom I find it hard to find enough good things to say about. I’d recommend anyone considering herbal supplements to keep Gaia in mind.

Type: Consumer Brand

Price: Medium

Quality: High

Availability: Online, Direct, Local Stores

Parent Company: Gaia Herbs, Inc.

Gaia Herbs Supplement Logo Banner Optimus Medica
Gaia Herbs is one of my favorite herbal supplement brands in the world. Their WNC-based farm helps them formulate some of the most potent, natural, and efficacious products on the market. They are a model for quality and formulation within the supplements market and I'd recommend them to anyone considering an herbal supplement.
5
Rating
Available Online

Douglas Laboratories

Douglas Laboratories has a great product catalog with a strong focus on sports nutrition. They have a product line (technically a separate brand) called Klean Athlete that sells only NSF Certified for Sport products. Douglas Laboratories is an NSF Registered GMP company whose facility is also NSF Certified for Sport. Their products are self-certified as Non-GMO. My experience with Douglas Labs has been primarily with their amino acid supplements, which I find to often be the best value in terms of price vs. quality.

Type: Practitioner Brand

Price: High

Quality: High

Availability: Doctor, Authorized Reseller

Parent Company: Atrium, Inc (Nestle, Inc. Subsidiary)

douglas-laboratories-supplements-logo
4.5
Rating
Available Online

Garden of Life

Garden of Life has a large catalog full of products that are focused on organic and certified Non-GMO whole food ingredients. Their supplements are formulated to ensure the natural cofactors and enzymes found with certain compounds are included to maximize bioavailability. Garden of Life supplements are third-party certified to be Organic and Non-GMO and are produced in an NSF Certified for Sport facility. I can’t think of a better whole-foods based supplement brand on the market today.

Type: Consumer Brand

Price: High

Quality: High

Availability: In stores and Online

Parent Company: Atrium, Inc (Nestle, Inc. Subsidiary)

Garden of Life Supplements
Available Online

Jarrow Formulas

Jarrow has a very large category featuring just about any supplement one could hope to find. They’re a consumer brand but I’ve been in many practitioner offices that sell their products directly. Many of their amino acid and nootropic products can be found in local stores such as The Vitamin Shoppe and Whole Foods. They are NSF Registered GMP, feature many NSF Certified Non-GMO products, and maintain their own dedicated production facilities. I’ve had a great experience with the L-Theanine, L-Glutamine, Reduced Glutathione, and 5-HTP products in the past.

Type: Consumer Brand

Price: Medium

Quality: Medium

Availability: Online, Direct, Local Stores

Parent Company: Jarrow Industries Inc

jarrow-formulas-supplements
Jarrow Formulas has a long history of dedication to quality nutritional products. Their catalog features everything you could imagine from sports medicine to early childhood vitamins. I've found their nootropics and amino acid products to offer particularly high value.
4.5
Rating
Available Online

Bluebonnet

Bluebonnet operates with a mission of keeping ingredients as close to their whole-foods form as possible. They operate their own NSF Registered-GMP facility and many of their products are either NSF Non-GMO, USDA Organic, or Project Non-GMO certified. I’ve found their mineral, vitamin, and amino acid supplements (particularly their N-Acetyl Cysteine) to be very potent. I also like that their products all come in amber glass bottles to avoid residual toxins and preserve purity.

Type: Consumer Brand

Price: Medium

Quality: Medium-High

Availability: Online, Direct, Some Local Stores.

Parent Company: Bluebonnet Nutrition Corp.

blue bonnet nutrition logo
Bluebonnet Nutrition is an exemplary supplement brand that features a catalog of products certified to be USDA organic, Project Non-GMO, and NSF cGMP quality. Bluebonnet products are made with the goal of keeping ingredients as close to their whole food form as possible.
5
Rating
Available Online

Standard Process

Standard Process stands apart from many supplement manufacturers in that they grow many of their own ingredients. Their sustainable farming and production practices make them one of the best whole-foods vitamin brands around. Standard Process might not be a great choice for those with food sensitivities considering their ingredients panels read like grocery lists. I’d recommend them to anyone looking for a whole-foods based product.

Type: Practitioner Brand

Price: High

Quality: High

Availability: Doctor, Online

Parent Company: Standard Process, Inc.

standard process supplements logo
Standard Process is an incredible whole-foods based supplement brand that's family-owned and dedicated to sustainable manufacturing practices.
4
Rating
Available Online

Klaire Labs

Klaire Labs specializes in probiotics but also offers many other products. Their probiotics are the most highly-regarded, generally speaking, among most health practitioners I’ve spoken with. They have formulations for detox, everyday support, and more specific concerns as well. Their products are available online but—if you’re ordering probiotics—make sure the seller ships them in refrigerated containers!

Type: Practitioner Brand

Price: High

Quality: High

Availability: Doctor, Authorized-Reseller

Parent Company: Soho Flordis International Pty Limited (SFI Int’l)

klaire labs supplements logo optimus medica
Klaire Labs offers an incredible catalog of potent probiotics manufactured to offer the most powerful results possible. Their dedication to quality and scientific formulation has earned them a stellar reputation among health professionals.
5
Rating
Available Online

Vital Nutrients

Vital Nutrients works closely with health professionals around the world to develop powerful nutritive supplements. Their product catalog features isolate compounds, blends based on the latest clinical research, and products designed to address specific health concerns. I’ve been a tremendous fan of their mineral products over the years and believe they have the best deal in town for lithium orotate (know for its neuroprotective benefits.)

Type: Practitioner Brand

Price: High

Quality: High

Availability: Doctor, Authorized-Resellers, Direct

Parent Company: RHG & Company, Inc

Vital Nutrients Supplements Logo
Vital Nutrients have a catalog of scientifically-formulated supplements and nutrition products designed to offer nutritive support to even the most complicated of cases. Their supplements are produced in an FDA-Registered and inspected facility in accordance with the latest cGMPs.
4
Rating
Available Online

Ecological Formulas

Ecological Formulas, a subsidiary or Cardiovascular Research, specializes in products designed to support metabolic and vascular health. Over the past 20 years, their catalog has evolved to include many other products as well. I’ve found their mineral supplements and immune-boosting products to fall within an incredible range of price vs. quality.

Type: Practitioner Brand

Price: Medium

Quality: High

Availability: Online, Local Stores

Parent Company: Arterio, Inc.

ecological-formulas-supplments-logo-banner-optimus-medica
Ecological Formulas boasts a catalog of high-quality supplements that often come in lower-priced than most consumer brands. They are my go-to supplement brand for many mineral products but offer something for everyone out there.
4.5
Rating
Available Online

KAL

KAL has been around since th3 1930s and specializes in mineral blends. They are one of my favorite store brands and adhere to GMP standards, though they aren’t third-party certified. Their chelated magnesium, calcium, and zinc supplements are particularly popular. One of my favorite aspects of the KAL brand, besides being a trustworthy in-store brand, is that their minerals are available in many different forms.

Type: Consumer Brand

Quality: Medium/High

Price: Medium

Availability: Online, Local Stores

Parent Company: Nutraceutical Corporation

kal supplements logo on background optimus medica
KAL has been around for nearly 80 years. They offer a great lineup of mineral supplements, are available at most local retailers, and are very reasonably priced.
4.5
Rating
Available Online

Solaray

Solaray products are a great option when shopping in local stores. Their products are produced under cGMP guidelines and avoid using artificial flavoring, sweetening, or preservatives, though their manufacturing facilities are not NSF GMP-Registered. Solaray supplements offer a wide-ranging catalog with a strong focus on botanical and herbal blends but also includes such products as probiotics, minerals, and vitamins.

Type: Consumer Brand

Quality: Medium/High

Price: Medium

Availability: Online, Local Stores

Parent Company: Nutraceutical Corporation

solaray supplements logo banner optimus medica
Solaray produces a quality lineup of supplements free of artificial preservatives, sweeteners, and flavoring. They adhere to cGMP manufacturing practices and are one of the best supplement brands available in local stores.
4.3
Rating
Available Online

Integrative Therapeutics

Integrative Therapeutics is a doctor-trusted supplement brand whose products are developed under the guidance of a scientific advisory board. Integrative Therapeutics operates its own NSF Certifed GMP facility that is also certified to produce OTC-quality products. This is a step above other high-quality supplement brands. I’ve had a very positive experience with their products over the years and have had many health professionals express the same sentiment to me.

Type: Practitioner Channel

Quality: High

Price: High

Availability: Doctor, Authorized Re-Sellers

Parent Company: Schwabe North America

integrative therapeutics supplements logo optimus medica banner
Integrative Therapeutics is a doctor-trusted supplement brand with a track record of impeccable quality. They operate an NSF Certified GMP facility and I've had a very positive experience with any of their products I've tried over the years.
4.8
Rating
Available Online

Nature’s Way

Nature’s Way has an incredible catalog of high-quality botanical supplments that range from single ingredient isolates to full herbal blends. Many of their products are TRU-ID verified (DNA-verified ingredients) and Project Non-GMO certified free of GMO compounds. Nature’s Way is NSF GMP-Registered and is one of my absolute favorite in-store brands. I’ve used their products for years and always trust them to deliver quality and potency.

Type: Consumer Brand

Quality: Medium to High

Price: Low to Medium

Availability: Online, Local Stores

Parent Company: Schwabe North America

nature's way supplement logo optimus medica
Nature's Way offers an incredibly pure and potent catalog of herbal supplements. Their products are TRU-ID verified and produced in an NSF GMP-Registered facility. They are among the highest-quality and lowest-priced supplements found in local stores.
5
Rating
Available Online

Xymogen

Xymogen makes some of the most targeted formulations I’ve ever come across. Every Integrative doctor I’ve ever been to relies on their products to deliver potent results. Their products are manufactured in an FDA registered, NSF Registered GMP, and NSF Certified for Sport facility. Xymogen is a practitioner-only brand that can only be purchased directly from a licensed medical professional or through their website with a code given to you by your doctor.

Type: Practitioner Brand

Quality: High

Price: High

Availability: Doctor

Parent Company: Xymogen, Inc

xymogen supplements logo banner optimus medica
Xymogen has a long record of producing quality nutritional supplements. They work closely with health practitioners to develop products that offer unmatched targeting for specific health concerns. They are NSF Registered GMP and also NSF Certified for Sport.
5
Rating
Practitioner Only

Biotics Research

Biotics Research has been a pioneer in the practitioner channel supplements market for nearly 40 years. Their products are as pure as they come, formulated for maximum efficacy, and trusted by doctors around the world. Biotics Research maintains its own manufacturing facility where they do exhaustive testing to ensure product quality and identity. Biotics Research supplements are available from health practitioners or directly from Biotics Research with a practitioner-provided registration code. You can find their products on Amazon but they are not from licensed resellers.

Type: Practitioner Brand

Quality: High

Price: High

Availability: Doctor

Parent Company: Biotics Research Corporation

biotics research supplements logo wallpaper optimus medica
Biotics Research is one of the most well-respected supplement brands among the health practitioners I've had the pleasure of working with over the years. Their supplements are only available directly from a licensed professional or from their website with an authorization code.
5
Rating
Practitioner Only

Resources

The vitamin and supplement brands listed here are the ones that I’ve come to know and love over the years. My best advice: do not believe a word I’ve written and learn to qualify quality brands yourself. I’ve put together a list of articles and resources that are meant to help anyone better understand how to find quality supplements.

cGMP & Dietary Supplement Manufacturing

NSF Certifications for Dietary Supplements

USP Guidelines for Dietary Supplements

Vitamin & Supplement Buyer’s Guide